Posts by: Patricia Inacio, PhD

News

In a new study entitled “Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials” researchers at The University of Texas ... Read more

July 1, 2015July 8, 2015

Novel Antibody Increases Squamous NSCLC Patients’ Survival

News

In a new study entitled “Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, ... Read more

May 31, 2015

Chemotherapy Combined With Anti-PDL1 Antibody Shows Promising Results in Advanced Lung Cancer

News

A recent phase 1b study showed that combining standard chemotherapy with an antibody targeting the protein PDL1, short for programmed death-ligand 1 and whose key function is to suppress the immune system, yields ... Read more

April 10, 2015April 10, 2015

Study Finds Protein Boosts Cancer Stem Cell Renewal in NSCLC

Lung cancer News, News

In a recent study entitled “YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate self-renewal and Vascular Mimicry of Stem-like Cells” researchers show how YAP1 protein promotes lung cancer stem ... Read more

March 9, 2015March 9, 2015

Efficient Targeted Delivery of Chemotherapy-Loaded Nanoparticles to Lung-Tumors

News

In a new study entitled “Protease Mediated Release of Chemotherapeutics From Mesoporous Silica Nanoparticles to Ex Vivo Human and Mouse Lung Tumors” researchers engineered nanoparticles loaded with chemotherapeutics that specifically target ... Read more

March 4, 2015March 4, 2015

TGF-β is a Key Driver of Tumor Heterogeneity, Drug Resistance in Lung & Other Cancers

Lung cancer News, News

In a new study entitled “TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma,” researchers at The Rockefeller University discovered TGF-β is a key driver of tumor heterogeneity and ... Read more

March 2, 2015March 2, 2015

Graphene Inhibits Lung Cancer Stem Cells’ Proliferation

News

In a new study entitled “Graphene oxide selectively targets cancer stem cells, across multiple tumor types: Implications for non-toxic cancer treatment, via “differentiation-based nano-therapy” researchers showed that graphene oxide, a nanomaterial, specifically ... Read more

February 12, 2015February 12, 2015

Phase II Trial Will Test Pembrolizumab in Oligometastatic Lung Cancer Patients

Lung cancer News, News

A phase II clinical trial for patients with oligometastatic lung cancer will test the new immunotherapy drug pembrolizumab. This drug acts specifically on T cells and blocks the programmed death receptor (PD-1) ... Read more

February 4, 2015February 4, 2015

Mutation in Parkinson’s Gene Associated With Lung Cancer Susceptibility

News

In a new study entitled “A Recurrent Mutation in PARK2 Is Associated with Familial Lung Cancer” a team of researchers found that a germline mutation in a gene associated with ... Read more

January 12, 2015January 12, 2015

Researchers Discover Key Gene Involved In Lung Cancer Progression

News

A new study entitled “The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling” discovered a key mediator of TGF-β signaling in tumors, the kinase BUB1. The study was ... Read more